Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Friday, December 2, 2016

New method to restore function of white blood cells in septic patients

New research findings published in the Journal of Leukocyte Biology, suggest that treating the white blood cells of sepsis patients with antibodies that block programmed cell death-1 (PD-1) and programmed cell death ligand (PD-L1) molecules may restore their function and ultimately their ability to eradicate deadly bacteria.

"We hope that this study will lead to a better understanding of why patients with sepsis are often unable to successfully eradicate invading microorganisms," said author Andriani C. Patera, Ph.D. "Furthermore, we hope that this study will stimulate new therapies to treat sepsis based on stimulating various components of the immune system."

Read more:
Scientists discover new method to restore function of white blood cells in septic patients

Source: EurekAlert! Science News

Tuesday, November 29, 2016

Free guide to quantify uncertainty

Quantifying Uncertainty in Analytical Measurement, 3rd Edition

Eurachem guide provides explicitly for the use of validation and related data in the construction of uncertainty estimates in full compliance with the formal ISO Guide principles set out in the ISO Guide to the Expression of Uncertainty in measurement. The approach is also consistent with the requirements of ISO/IEC 17025:2005.

Read more:
Quantifying Uncertainty

Source: Eurachem

Plasma Creatinine Poor Predictor of Acute Kidney Injury in Pediatric ICU

Acute kidney injury develops in more than one quarter of children and young adults admitted to intensive care units. And in severe cases, it increases the odds of death by 77%, according to a new international observational study conducted in 32 hospitals.

The analysis, reported Friday at the annual meeting of the American Society of Nephrology in Chicago and online by the New England Journal of Medicine, also found that plasma creatinine, by itself, was not an effective method for diagnosing the problem. It failed in 67.2% of patients with low urine output.

Read more:
Creatinine Poor Predictor of Acute Kidney Injury in Pediatric ICU

Soure: MedScape

Sunday, November 27, 2016

Just Science

Beautiful drawing by Saranya Singaravel


Source: Twitter via Saranya Singaravel

Platelet Activation and Factors for Clot Formation

Great animation of coagulation process

View in YouTube
Platelet Activation and Factors for Clot Formation


Source: YouTube

Should you have a break every now and then?

Microscope work involves sustained static postures of the head, neck and body. Adjust your workstation to minimize awkward postures and improve comfort. Risks are
  • Forward bending-strains back musculature
  • Leaning on arms-strains upper shoulders/neck
  • Forearm contact pressure on table top

Learn how to improve ergonomics at microscope work:
Microscope Ergonomics

Source:UBC Human Resources
Image: Facebook via Trust me I´m a biologist

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