Researchers from the Mayo Clinic in Rochester, MN analyzed stool samples from 320 patients showing no symptoms of C. difficile at hospital admission using a real-time polymerase chain reaction (PCR) assay. Samples from 31 of 320 patients tested positive for C. difficile, resulting in a colonization rate of 9.7 percent. The authors wanted to estimate the reservoir of colonized patients as a source of potential transmission because despite rigorous infection control measures, C. difficile infection was increasing at their institution.
Targeted Screening for C difficile Upon Admission Could Potentially Identify Most Colonized Patients
Art and Science of Laboratory Medicine
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