Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Saturday, November 9, 2013

Chediak-Higashi–like granules within leukemic promyelocytes

A 59-year-old woman with disseminated intravascular coagulation was transferred after a dose of growth factor for “leukopenia.” Laboratory studies showed elevated d-dimer (201 934 ng/mL), with a white blood cell count of 41 000/mm3 (blasts, 19%; promyelocytes, 37%) and platelets of 49 000/μL, at which time all-trans-retinoic acid (ATRA) had already been instituted owing to a high suspicion of acute promyelocytic leukemia (APL). 

Read more:
Chediak-Higashi–like granules within leukemic promyelocytes



















Source: Blood
Image credits: Blood/ hematology library


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