Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Monday, March 3, 2014

A Complete Medical Check-up On a Chip

About the size of a stapler, this new handheld device developed at EFPL is able to test a large number of proteins in our body all at once-a subtle combination of optical science and engineering.

Only 7.5 cm high and weighing 60 grams, the device is able to detect viruses and single layer proteins down to 3 nanometers thick. Detailed in a publication in Nature Light Science & Application, the recipe is simple and contains few ingredients: an off the shelf CMOS chip, a light-emitting diode (LED) and a 10 by 10 millimeter gold plate pierced with arrays of extremely small holes less than 200 nanometer wide.

Nanoholes on the gold substrates are compartmented into arrays of different sections, where each section functions as an independent sensor. Sensors are coated with special biofilms that are specifically attracting targeted proteins. Consequently, multiple different proteins in the biosamples could be captured at different places on the platform and monitored simultaneously.

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A Complete Medical Check-up On a Chip
























Source: News Mediacom

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