Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Saturday, October 18, 2014

Lymphoproliferative disorder with Auer rod–like inclusions

The patient is a 92-year-old woman who presented to the hematology clinic 3 years earlier for evaluation of persistent lymphocytosis. At that time, her white blood cell count was 15 200/µL, hemoglobin was 12.8 g/dL, and platelets were 245 000/µL. Her absolute lymphocyte count was 7870/µL. She did not have lymphadenopathy or hepatosplenomegaly on physical examination.

This case highlights a rare example where the presence of Auer rod–like inclusions does not automatically denote myeloid differentiation. To the best of our knowledge, the presence of Auer rod–like lymphocyte inclusions has been previously reported only in a single case of a peripheralizing marginal zone lymphoma from Japan.

Read more:
Lymphoproliferative disorder with Auer rod–like inclusions

Source: Blood Journal

1 comment:

susanne widell said...

Nice Photo! This might be seen in MDS cases were a very early progenitor mixed for the myeloid as well as the lymphoid lineages is involved in the leukemia. S.Widell

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