A new study from researchers in Japan has identified features that appear to be responsible for bacteria becoming resistant to antibiotics. The investigators examined genetic and phenotypic changes in 44 antibiotic-resistant strains of Escherichia coli (E. coli). In their findings, which were published in Nature Communications, the researchers found that antibiotic resistance occurs through mutations that converge on similar physical changes in the bacteria.
The researchers examined strains of E. coli that were each resistant to 1 of 11 different antibiotics and observed how each of the 44 strains responded to 25 antibiotics.
E. Coli Strains Shed Light on Antibiotic Resistance
Image credits: Tom M notthattom