As any good bench technologist knows, quality is in the details. But details bedevil quality in sources of error that affect the precision and accuracy of test results. In labs where automation is common and less sample handling is required for hands-on testing, light microscopy is still fraught with human error. Understanding sources of microscopic variation in hematology will help you develop a strategy that improves quality.
Generally, sources of error arise from preanalytical, analytical, or post-analytical phases that can create variation throughout the microscopic process. These errors may be random or systematic. A comprehensive quality program considers these sources of error and contains strategies to detect and correct process-related errors.
Reducing Microscopic Variation